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Analysis of institutional authors

Veses Jimenez, VerónicaCorresponding AuthorSheth CcAuthor

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July 14, 2020
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Herbal Extracts with Antifungal Activity Against Candida albicans: A Systematic Review

Publicated to:Mini-Reviews In Medicinal Chemistry. 21 (1): 90-117 - 2021-01-01 21(1), DOI: 10.2174/1389557520666200628032116

Authors: Hsu, Hsuan; Sheth, Chirag C; Veses, Veronica

Affiliations

Department of Biomedical Sciences, Faculty of Health Sciences, Universidad Cardenal Herrera, CEU Universities, Moncada 46113, Valencia. Spain. - Author
Department of Dentistry, Faculty of Health Sciences, Universidad Cardenal Herrera, CEU Universities, Moncada 46113, Valencia. Spain. - Author
Department of Medicine, Faculty of Health Sciences, Universidad Cardenal Herrera, CEU Universities, Moncada 46113, Valencia. Spain. - Author
‎ Univ Cardenal Herrera, CEU Univ, Fac Hlth Sci, Dept Biomed Sci, Valencia 46113, Spain - Author
‎ Univ Cardenal Herrera, CEU Univ, Fac Hlth Sci, Dept Dent, Valencia 46113, Spain - Author
‎ Univ Cardenal Herrera, CEU Univ, Fac Hlth Sci, Dept Med, Valencia 46113, Spain - Author
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Abstract

In the era of antimicrobial resistance, fungal pathogens are not an exception. Several strategies, including antimicrobial stewardship programs and high throughput screening of new drugs are being implemented. Several recent studies have demonstrated effectiveness of plant compounds with antifungal activity.In this systematic review we examine the use of natural compounds as a possible avenue to fight fungal infections produced by Candida albicans, the most common human fungal pathogen.Electronic literature searches were conducted through PubMed/MEDLINE, Cochrane, and Science Direct limited to the 5 years. A total of 131 articles were included with 186 plants extracts evaluated.Although the majority of the natural extracts exhibited antifungal activities against C. albicans (both in vivo and in vitro), the strongest antifungal activity was obtained from Lawsonia inermis, Pelargonium graveolens, Camellia sinensis, Mentha piperita, and Citrus latifolia.The main components with proven antifungal activities were phenolic compounds such as gallic acid, thymol, and flavonoids (specially catechin), polyphenols such as tannins, terpenoids and saponins. The incorporation of nanotechnology enhances greatly the antifungal properties of these natural compounds. Further research is needed to fully characterize the composition of all herbal extracts with antifungal activity as well as the mechanisms of action of the active compounds.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Keywords

Antifungal agentsAntifungal propertiesAntimicrobial activityAntioxidant activityBiofilm formationBiological-activitiesCamellia sinensisCandida albicansCatechinChemical-compositionCitrusEssential oilGallic acidHerbal extractsHumansIn-vitro evaluationLawsonia plantLeaf extractsMedicinal-plantsMentha piperitaMicrobial sensitivity testsNanotechnologyPelargoniumPhytochemical characterizationPlant extractsThymol

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Mini-Reviews In Medicinal Chemistry due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2021, it was in position 31/63, thus managing to position itself as a Q2 (Segundo Cuartil), in the category Chemistry, Medicinal. Notably, the journal is positioned en el Cuartil Q2 para la agencia Scopus (SJR) en la categoría Medicine (Miscellaneous).

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 2.43. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 2.25 (source consulted: FECYT Feb 2024)
  • Field Citation Ratio (FCR) from Dimensions: 10.47 (source consulted: Dimensions Jul 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-07-18, the following number of citations:

  • WoS: 37
  • Scopus: 42
  • Europe PMC: 8

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-07-18:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 128.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 107 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 24.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).
  • The number of mentions in news outlets: 3 (Altmetric).

Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Hsu H) and Last Author (Veses V).

the authors responsible for correspondence tasks have been Veses Jimenez, Verónica and Veses V.